NFL Underdogs: NFL Odds, Picks and Predictions Week 16

We’re making a list and checking it twice. We’re going to find out… just who the hell is playing in NFL Week 16.

The pandemic is crashing Christmas weekend with Grinch-like ferocity, stealing away your best-laid plans for the holidays and, as well, handicapping the NFL Week 16 odds. 

Any NFL Underdogs point spread picks we get down early run the risk of being flipped on their ear, with outbreaks popping up like festive cheese-and-meat kiosks at the mall. And with the league tweaking its rules around vaccinated players, availability is just a big mystery box to be opened in a final hours before kickoff.

Roger Goodell is giving off major Clark W. Griswold vibes in the home stretch of the schedule. But instead of staring through crazy eyes and pushing through as his “fun, old-fashioned family Christmas” burns to the ground around him, Goodell is dead-set on putting a product on the field for the next three weeks.

And if there’s football. We’re going to bet on it. Here are my favorite NFL Week 16 picks getting the points this holiday weekend. Good luck and be safe.

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